mRNA-LNP

Ionizable Lipids

 

A series of novel ionizable lipids have developed and applied to mRNA-LNP delivery.

In vitro and In vivo, these lipids exhibit the high binding affinity, acceptable encapsulation efficiency (EE) and suitable polydispersity index (PDI). 

Some of those lipids have been carried out Non-GLP Genotoxicity (Ames Test) and 14-days single dose toxicity studies.

 

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