Human antibody mouse
AcadeMab’s antibody mouse is developed by the replacement of the original mouse antibody genes to human antibody genes. This mouse strain can generate human antibodies that have been optimized naturally through in vivo affinity maturation. It can generate a wide variety of therapeutic antibodies from the transgenic mouse via hybridoma cell or single B cell selection. Therefore, it is a powerful tool to provide highly productive, developmental, and customized therapeutic antibodies to the global biopharmaceutical industry.
Feature
- The human antibodies can be generated via conventional hybridoma technology, which is user-friendly.
- The antibody affinity maturation can naturally occur, leading to high affinity clones, via the immunization and boosting of the exotic antigen.
Application
For developing therapeutic antibodies against specific antigen or pathogen via either hybridoma technology or single B cell selection.